The variable R group gives rise to the four most commonly known cobalamins: cyanocobalamin (CNCbl), methylcobalamin (MeCbl), adenosylcobalamin (AdCbl, also known as cobamamide or 5-deoxyadenosylcobalamin), and hydroxocobalamin (OHCbl)
In addition, people with gastrointestinal issues that prevent absorption of nutrients from the gut can develop vitamin B12 deficiency symptoms
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This may be due to the low level of expression of these proteins, which are not encoded by subgenomic RNAs or present within the virion
Scientists are still studying 5-Amino-1MQ, but early research is promising