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Indeed, chronic alcoholism and nicotine consumption are independent risk factors for pancreatitis, and both inhibit pancreatic thiamine uptake via downregulation of thiamine transporters (90)

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Statins remain the first-line treatment for elevated cholesterol with decades of robust evidence, whilst Ozempic's effects on cholesterol are modest, indirect, and secondary to its diabetes indication

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Small-molecule mechanism distinct from incretin therapies

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