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In general, essential fatty acid deficiency (i.e., deficiency of both ALA and LA) has been observed only in patients with chronic fat malabsorption, cystic fibrosis, or those on parenteral nutrition without PUFA (86, 95) (see the article on Essential Fatty Acids)
If youre experiencing symptoms such as fatigue, low energy, mood changes, or tingling in your hands and feet, a B12 deficiency could be the cause
10.1038/s41569-019-0265-3 219
Thymosin Beta-4 has been studied in Phase II clinical trials for corneal wound healing, where it showed a 59% reduction in corneal staining compared to placebo
Up to 70% increase in collagen production
The theoretical safety consideration he raises relates to both peptides promoting angiogenesis
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