Chinnery, PF, Turnbull, DM 2001, Epidemiology and treatment of mitochondrial disorders, American Journal of Medical Genetics , vol
Supporting clinical documentation including lab results (HbA1c for diabetes, lipid panels, liver function tests), anthropometric measurements (weight, height, BMI, waist circumference), comorbidity documentation, and records of previous treatment attempts
Furthermore, ferulic acid treatment in a mouse model of neuroinhibition reduces p-JNK, p-NFB in glial cells of the mouse hippocampus and activates mitochondrial apoptotic molecules (Bax, cytochrome c, caspase-3, and PARP-1) in small/medium glial cells to induce anti-inflammatory effects by interfering with the TLR4/MD2 complex binding site (Nagarajan et al., 2015)
For Lebers optic atrophy or smokers blindness, the usual dose starts at 1000mcg, given daily for 2 weeks, followed by twice weekly
Jul 2016;96(3):873-909
The main one that we use and find helpful is methylcobalmin