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usually mild-to-moderate and easing over time [1]
The TNF- concentration of 200 ng/ml had the best inhibitory effect
PepGen developed a POC drug, PGN-EDO51, using its enhanced delivery oligonucleotide platform, which skips exon 51 in the DMD gene
This inhibition resulted in a two-fold increase in GJ expression in the liver compared to wild-type mice (Hsu et al
Dark spots o kome geche
(2001) Mechanism and significance of increased glutathione level in human hepatocellular carcinoma and liver regeneration, FASEB J
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