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SA was added to every related experiment group unless otherwise specified
No head-to-head randomized controlled trial comparing Retatrutide vs Tirzepatide directly has been published as of 2026, making direct efficacy comparisons inferential based on cross-trial data
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The number needed to treat to prevent one major adverse cardiovascular event after one and three years of use was 378 and 131, respectively
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Another prevalent issue is gallbladder disease
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