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In addition, APE1 was also upregulated in astrocytes and spinal cord white matter in ALS patients (Shaikh and Martin, 2002)
In peer-reviewed animal work the concrete numbers are oral doses of roughly 1.442.88 mg/kg given daily to APP/PS1 Alzheimer-model mice over about three months [3] , and low-mg/kg dosing that reversed scopolamine-induced deficits in rodents [1]
Recommendation: Test b12, but do not wait for results to make changes
Your mineral supply is largely determined by your diet
Biofactors 45:930943
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