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Cardiovascular outcome trials of tirzepatideSURPASS-CVOT and SUMMIThave shown encouraging signals, with SURPASS-CVOT meeting the prespecified criteria for non-inferiority for MACEs and a 16% reduction in all-cause mortality [86]

Ethics approval All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards

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From there, you can file an internal appeal with your insurer, ideally supported by a letter of medical necessity from your provider

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