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For example, exosomal circUSP7 from NSCLC cells inhibits miR-934 in CD8 T cells, upregulates SHP2, suppresses effector cytokine secretion (e.g., TNF-, IFN-), and induces T-cell exhaustion, thereby impairing anti-PD-1 efficacy

Mirjalili, M., Mirzaei, E

36.2% As per dosage form, the single-dose pen segment is expected to dominate, contributing to the global Mounjaro market in 2026

Kynurenine acts as a signaling molecule to attenuate pulmonary fibrosis by enhancing the AHR-PTEN axis

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