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Mechanically, GLP-1RAs regulate insulin-like growth factor-1/2 and upregulate -estrogen receptors to exert cardioprotective actions in isoprenaline-induced MI [73]

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Possible signs of excess copper may include: Nausea Metallic taste Digestive upset Headaches Mood changes Anxiety or irritability Insomnia Fatigue With more significant chronic excess, concerns may include elevated liver enzymes or neurologic symptoms

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