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Secondary endpoints included the proportion of participants achieving 5% and 10% body weight reduction, absolute weight change in kg, change in waist circumference, lipid parameters including total cholesterol, HDL, LDL, VLDL, triglycerides, and glycaemic variables such as HbA1c, fasting glucose, insulin, HOMA-IR, and -cell function

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Substrate injection was as follows: 4 mM ADP at port A, 10 M oligomycin at port B, 10 M FCCP at port C and 10 M antimycin A at port D

In de praktijk worden GLP-1-receptoragonisten gebruikt voor de behandeling van diabetes en obesitas