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Morphological studies demonstrated a particularly high density of GLP-1R expression in the PVN of mice (Merchenthaler et al., 1999
GLP-1RA may also lower blood pressure through effects on the endothelium, and increase heart rate (HR) through stimulation of the sinoatrial node and the sympathetic nervous system (SNS) 33 , 34
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Chez les porteurs de mutations lies cette maladie, un suivi rgulier est crucial pour viter des complications neurologiques
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