Since the body cannot produce vitamin B12 itself, it is dependent on absorption through food
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Clean the injection site with alcohol, allow to dry, pinch the skin lightly if needed, insert the needle at a 45 to 90 degree angle depending on tissue depth, and inject slowly
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Clinicians should also avoid or adjust therapy in individuals with active peptic ulcer disease due to theoretical choline-mediated increases in gastric volume and in those receiving levodopa, as pantothenic-acid derivatives may interfere with levodopa absorption