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Participants maintained their weight loss at 6-month follow-up, suggesting the metabolic benefits persist beyond active treatment

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Hydroxocobalamin might stay in the body longer

Note: It's important to rotate injection sites, as repeated injections into the same location can cause scarring and hardening of the fatty tissue, making future injections more difficult and interfering with absorption of the medication

Pairing semaglutide with vitamin B12 is done to help reduce appetite while also supporting energy and metabolism

There is no digestive step and no intrinsic factor requirement, which is the entire point for anyone whose absorption is compromised