Managing Digestive Side Effects Naturally While probiotics are a powerful tool, they work best when combined with other gut-supportive habits
Alcohol tolerance changes significantly during GLP-1 treatment, often making people much more sensitive to its effects than they were before.(10) This is worth knowing for occasions when drinking is part of the plan, so expectations can be adjusted without awkwardness
Pool of Seven Controlled Clinical Trials Adverse reactions were also evaluated in a larger pool of adult patients with type 2 diabetes mellitus participating in seven controlled clinical trials which included two placebo-controlled trials (SURPASS-1 and -5), three trials of MOUNJARO in combination with metformin, sulfonylureas, and/or SGLT2 Inhibitors (SURPASS-2, -3, -4) [see Clinical Studies (14.3)] and two additional trials conducted in Japan
I joined MDWatch in March 2025 at 246 lbs
Disclaimer: This list is not comprehensive
Some common side effects of GLP-1s include diarrhea, nausea and bloating but they often go away in the first day or two after taking the medication as prescribed