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Vitamin B12 Supplementation: Preventing Onset and Improving Prognosis of Depression. Cureus, vol
doi:10.3390/jcm7100304
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This article compares mechanism, Phase 2 trial design, reported efficacy, tolerability signals, and research-use status
Importantly, these effects occur without activation of growth hormone receptor pathways or alteration of IGF-1 signaling, allowing AOD 9604 to be used as a tool for isolating metabolic signaling mechanisms
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