Report any signs of depression, anxiety, or suicidal thoughts immediately
One dynamic that we and investors will be closely monitoring is the potential tailwind to branded GLP-1 drugs for obesity when compounded versions can no longer be sold in the US, as of May 22, 2025
Taken together, this means youre most likely to notice shedding 2-3 months after starting a GLP-1
otherwise contact NHS 111, your local NHS urgent mental health helpline, or Samaritans on 116 123 ) Marked changes in behaviour that concern you or those close to you Any side effect that significantly impacts your quality of life Your GP can : Assess whether symptoms may be related to the medication or other factors Review your overall mental health and screen for depression or anxiety disorders Consider dose adjustment or alternative diabetes management strategies Refer you to mental health services if appropriate In line with NICE guidance for type 2 diabetes (NG28), you should have HbA1c checks every 36 months until stable, then every 6 months, plus at least one comprehensive annual diabetes review
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Incorporating lean protein sources and small portions of healthy fats, such as avocados and nuts, into your Wegovy diet plan might help some people reduce or avoid these side effects