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According to Rubino, clinical trials are now being planned to assess whether higher doses of GLP-1 drugs can be used in the acute phase to help patients lose weight, followed by lower "maintenance" doses, which come with fewer side effects and can be prescribed on a long-term basis
Adv Mater 30 Wang S, Zhang Q, Hui H, Agrawal K, Karris MAY, Rana TM (2020) An atlas of immune cell exhaustion in HIV-infected individuals revealed by single-cell transcriptomics
GLP-1 receptor agonists are different
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