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The clinical and economic implications of indefinite treatment are considerable, driving innovation in approaches that might allow successful maintenance without continuous medication or that could extend dosing intervals substantially
Separately, a national survey of aesthetic providers reported that the number of patients arriving on these medications more than doubled between 2023 and 2024, with midface volume loss, skin laxity, and deepening folds cited as the concerns providers saw most
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At prescription-level doses, it can help lower your circulating levels of bad LDL cholesterol, improve good HDL cholesterol levels and decrease triglyceride (fat) levels
The exception: in March 2024, the FDA approved a supplemental indication for semaglutide 2.4 mg (Wegovy) to reduce the risk of cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke in adults with established cardiovascular disease and either obesity or overweight (SELECT trial, Lincoff et al., New England Journal of Medicine 2023)
Not to exceed the recommended daily usage
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