Semaglutide mimics the effects of incretin hormones, giving you a huge weight-loss advantage
In patients with type 2 diabetes, the medication also improved glycemic management
In CD, its pro-inflammatory LPS suppresses the bile acid transporter ASBT via TLR4 and MAPKc-Jun/c-Fos signaling, impairing bile acid reabsorption and exacerbating Clostridioides difficile infection (Yang et al., 2025)
Engelman JA, Zejnullahu K, Mitsudomi T, Song Y, Hyland C, Park JO, et al
The FDA has listed the numerous medicines currently under deficiency
the clearest signal from trials and regulators points to gastrointestinal side effects like nausea and diarrhoea, which follow from GLP-1 action on the gut