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The risk of hypoglycemia with GLP-1 RAs is low when used as monotherapy

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This effect could be particularly problematic in patients with pre-existing conditions affecting gastric motility

Sinai Hospital receives funding for preclinical studies in the Drucker laboratory from Novo Nordisk and Pfizer Inc

Nutritional adequacy requires attention, as very-low-carbohydrate diets restrict many nutrient-dense foods including fruits, whole grains, and legumes

These new targets are being pursued to address the limitations of GLP-1s, particularly concerning muscle preservation and gastrointestinal side effects