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Gastrointestinal tolerance requires careful tracking, as nausea, vomiting, diarrhea, and constipation represent the most common adverse effects
A research study demonstrated that oral semaglutide (14mg) has more side effects than 1.2 mg subcutaneous liraglutide
However, this may change as Novo looks to expand its portfolio of weight loss drugs
The key adjustments are ensuring the eating window contains adequate protein, not extending fasting windows beyond 16 hours while on GLP-1 medication, and monitoring energy levels closely
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