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Urban tertiary hospital studies indicate even higher rates, frequently ranging from 31% to 45%, reflecting lifestyle transitions, socioeconomic factors and reduced physical activity in metropolitan areas. Obesity contributes to a spectrum of complications including type 2 diabetes mellitus, hypertension, dyslipidemia, coronary artery disease, osteoarthritis, obstructive sleep apnea and non-alcoholic fatty liver disease, thereby increasing all-cause mortality and posing significant public health challenges[4]

Practice Point 4.3.3: GLP-1 RA should not be used in combination with DPP-4 inhibitors

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Currently working on NAMS certification specializing in hormone replacement therapy

Tian, P

Therefore, amino acid metabolism linked to the liveralpha cell axis may also play an important role in GCGR mAb-induced beta cell regeneration