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PT-141 Investigations into Cavernous Tissues Studies have also explored PT-141 within the context of cavernous tissue physiology
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QMP engineering extends the plasma half-life of the GLP-1 albumin fusion Next, we examined whether QMP engineering of the GLP-1 albumin fusion would translate into extended plasma half-life, also after removal of L585
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Rats were run in two separate cohorts ( n = 56 per group/wave), where for each experimental test day rats received daily IP injections of vehicle, sCT (3 g/kg), liraglutide (50 g/kg), a combination of sCT and liraglutide (3 g/kg + 50 g/kg) or a stepwise administration of the amylin and GLP-1R analogs (rats received sCT treatment for the first week, liraglutide treatment for the second week, followed by a combination treatment of sCT + liraglutide daily for the remaining two weeks of testing)
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