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Subsequently in 1967, Samols and Marks reported glucagon-like material in pancreatectomized humans, indicating its extra-pancreatic origin (11)
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doi: 10.1038/s44161-024-00453-9
The therapeutic approach for HCC remains focused on curative treatments for early stages (resection, ablation, transplantation) or palliative systemic therapies for advanced disease (tyrosine kinase inhibitors [TKIs] and VEGF inhibitors) and immunotherapies (i.e., programmed death 1 [PD-1]/programmed cell death-ligand 1 [PD-L1] inhibitors and anti-cytotoxic T-lymphocyte-associated protein 4 [CTLA-4] antibodies) (Sadagopan et al., 2024
Nutritional deficiencies, including iron, folic acid, zinc, and vitamin B12
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