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Irisin, for example, enhances thermogenesis by promoting expression of brown-fat-related genes, which expend more energy than ordinary fat
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Early Phase I studies in humans identified 0.025 mg/kg per day (approximately 1.52 mg for an average adult) as an appropriate dose, with measurable tanning observed after just five low doses administered over two weeks [1]
Nat Publ Gr
Bibcode:2015PLoSO..1035268K
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