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ZakkarMVan der HeidenKLuongLAChaudhuryHCuhlmannSHamdulaySSet alActivation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state

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Nutritional folate deficiency combined more or less with the C677T MTHFR mutation may play an important role in basal hyperhomocysteinemia, whereas vitamin B 6 deficiency and heterozygosity for a CBS defect may only contribute to abnormal increment of postmethionine-load homocysteine levels (Ubbink et al, 1996)