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The study indicates that combining semaglutide with trevogrumab (anti-GDF8/anti-myostatin) helped prevent about half of the lean mass loss typically associated with GLP-1 therapy, while increasing fat loss

In the SURMOUNT-1 trials, the tirzepatide group lost about 20.2% of baseline body weight in 72 weeks, while the semaglutide group lost about 13.7 %

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Novo Nordisk: CagriSema Cagrilinitide is an analogue (a drug made to mimic a molecule already present in the body) of amylin, which acts as an agonist for calcitonin receptors