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In clinical trials, participants taking tirzepatide showed significant reductions in body weight compared to those taking other medications

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Non-GLP-1 oral medications (phentermine-topiramate, naltrexone-bupropion) are alternatives if GLP-1 therapy is not essential

Biochemical Pharmacology, 2024, DOI: 10.1016/j.bcp.2024.116565,

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This makes it an appealing option for individuals struggling with obesity or those requiring weight reduction for health reasons