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Briefly, an aliquot of cell homogenate was incubated with the labeled substrate DEVD-pNA (acetyl-Asp-Glu-Val-Asp p-nitroaniline), which is cleaved by the caspase-3 enzyme and releases the chromophore pNA
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Merad-Boudia M, Nicole A, Santiard-Baron D, Saille C, Ceballos-Picot I
It is studied for its anti-inflammatory effects via the melanocortin receptor system and through downstream inhibition of NF-B
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