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Wegovy is designed to be injected once a week

Less common but important risks include gallbladder disease, pancreatitis, and the boxed warning for medullary thyroid carcinoma based on rodent data

J Clin Pharmacol 58:158167 Allen J, Bradley RD (2011) Effects of oral glutathione supplementation on systemic oxidative stress biomarkers in human volunteers

Nonetheless, individuals with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia type 2 (MEN2) should discuss this with their clinician before enrolling in any trial involving this class of agent

Since in some of the studies analysed type 2 diabetic patients were treated with metformin, which has been shown to enhance GLP-1 responses [51], any potential difference in GLP-1 secretory responses between type 2 diabetic patients and healthy participants may have been modified by this mechanism

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