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Until then, every encouraging surrogate number comes with the same caveat: improvements in blood pressure, cholesterol, and triglycerides do not always translate to fewer real-world events

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Large-scale cardiovascular outcome trials involving tens of thousands of patients have provided reassuring safety data regarding malignancy

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doi: 10.1016/j.jfda.2016.10.016 430 KristoASKlimis-ZacasDSikalidisAK