what is the difference between glp-1 and glp-1/gip Biology of Incretins: GIP Explained: The Mechanisms of GLP-1

E.KadolskyU.KannambathS.VaikkinenH.FungK.DhamiP.et al (2023)

Mounjaro tends to win the Mounjaro vs Ozempic decision for patients who: Have obesity (BMI 30) or are overweight with metabolic risk factors, and weight loss is the primary goal Have an HbA1c that hasnt responded well to metformin or older GLP-1 drugs Dont have a strong personal or family history of cardiovascular disease that specifically needs Ozempics proven protective data Can sustain the higher monthly cost for the 12+ months typically needed for lasting results Who Should Consider Ozempic (or Generic Semaglutide)

However, tirzepatide does not directly target liver fat oxidation the way survodutide does

doi:10.1016/j.fertnstert.2018.01.029

J., Zou, Y., Harris, B

This case is notable because the patient had previously tolerated dulaglutide without any injection site reactions, emphasizing that tolerance to one GLP-1 agonist does not predict tolerance to another