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Multivariate analysis identified SOFA score, FiO 2 , and selenium increase as independent predictors of ICU mortality
This is one of the most efficient energy-producing pathways in cells, therefore, high energy demanding tissues, such as heart and kidney, mainly rely on fatty acids utilization (Console et al., 2020)
However, the largest Phase IIb trial involving 536 participants failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading to development termination in 2007
Kumar MMK, Madhavi K, Mohan T, Nagasree KP, Sangeeta GJ
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