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Naltrexone specifically blocks opioid receptors, which blunts alcohol's rewarding "buzz"it makes drinking feel less fun and less compelling

Where GLP-1 agonists like semaglutide work primarily through incretin-based signaling, cagrilintide approaches satiety from a completely different neurological pathway

It encourages the body to burn more fat and increases the energy it uses at rest

However, there has been no further development on this matter thus far

For the rest of the 1980s, the work he had done to find exendin-1 and exendin-2 lay just as dormant as the wasp hive that once adorned John Pisanos office at the NIH

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