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Burning that persists beyond 510 minutes, is accompanied by spreading redness or warmth that extends more than 1 inch beyond the injection site, or occurs alongside pus, drainage, or fever indicates possible infection and requires evaluation
[1] [3] The pivotal SURMOUNT-1 and SURMOUNT-2 clinical trials supporting Zepbound's approval lasted 72 weeks, with SURMOUNT-4 extending to 88 weeks total, demonstrating sustained weight loss throughout these periods
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