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Creatine without training does much less, and no trial has tested creatine specifically during GLP-1 therapy
If youre seeking general health support, the former may be enough but for more intensive needs, especially if youre pairing with NAD+, the latter is likely to be the better choice
Instead, their plausible contribution is indirect: by improving insulin sensitivity, reducing chronic low-grade inflammation, and supporting metabolic flexibility, postbiotics may enhance the efficiency of nutrient utilization and the anabolic response to protein and exercise
A few years ago, the idea that medications could help people lose between 10% and 20% of their body weight might have sounded overly optimistic
