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explain that SIRT1 deacetylation reorients FOXO3 from increasing the transcription of proapoptotic proteins to increasing the expression of stress response proteins such as GADD45 which, as per Tran et al
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(Lee told Undark that more research is underway, including one larger study and another with a comparison group.) If we do some certain studies, he said, the FDA may say, youve shown safety and efficacy. The agency, he added, might then allow the peptides to be compounded: Thats all were asking, he said