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The gold standard for comparing medicines is a robustly designed, well-conducted head-to-head clinical trial like Surmount-5, which remains the only head-to-head, randomized clinical trial directly comparing [the two drugs] in weight management, Lillys statement said

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Acknowledgments Under the direction of the authors, medical writing and editorial support, including the literature search, were provided by Graham Allcock of Axis, a division of Spirit Medical Communications Group Limited (funded by Novo Nordisk A/S)