is semaglutide or tirzepatide better for pcos PCOS? Tirzepatide is showing stronger results

While the safety of GLP-1 RAs is well established, current scientific evidence on the efficacy of microdosing GLP-1 RAs is lacking and further research is required to assess its benefits at lower doses

Prescription GLP-1 medications are not a substitute for prescribed medical treatment

J Transl Med 10:224

This oxytocin release may, in turn, modulate neurotransmission involving serotonin, glutamate, dopamine, and GABA, all of which are implicated in shaping social adaptation

That spiral now appears to be happening, the WHO reports

From a treatment perspective, the ups and downs associated with this could end up being hard to manage as, for example, insulin sensitivity may change in response to variation in Glucagon levels