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(1984): DSIP showed analgesic properties in chronic pain patients, with effects mediated through opioid receptor interactions
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This activation of the NRF2/SLC7A11/GPX4 pathway enhanced GSH levels, decreased lipid ROS accumulation, inhibited ferroptosis and lipid peroxidation, and improved the cognitive functions of AD mice ( In summary, Ghrelin, Neuritin, GAA, and Artemisinin may mitigate cerebral neuronal injury and cognitive dysfunction by modulating neuronal ferroptosis, lipid peroxidation, the antioxidant system, oxidative stress, mitochondrial dysfunction, and neuroinflammation
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