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The role of kinetic context in apparent biased agonism at GPCRs
Lipan, O
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This may include optimizing heart failure management, treating respiratory infections, adjusting asthma or COPD medications, or addressing sleep apnea with continuous positive airway pressure (CPAP) therapy
Warning signs include severe right upper quadrant pain (especially after meals), fever, jaundice (yellowing of skin or eyes), persistent nausea and vomiting, and dark urine with pale stools
The fourth hotspot is not previously correlated with the HGF binding site, which is across the plexinsemaphorin-integrin homology domain (PSI)-IPT 1 domains
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