A widely cited microarray screen reported that GHK exposure of human fibroblast cultures altered expression of more than 4,000 genes, with pathway analysis identifying TGF-, integrin, and ubiquitin-proteasome signaling as enriched among GHK-responsive transcripts
These findings are from preclinical research and have not been confirmed in human clinical trials
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Notably, various tumors, including BC, exhibit upregulation of specialized transporters such as membrane glycoprotein CD36 and fatty acid binding proteins (FABPs) [2]