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Abushanab D, Marquina C, Morton JI, et al

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Ongoing Monitoring At Each Follow-Up Visit: Ask specifically about tingling, numbness, burning sensations Check sensation in hands and feet Document any new symptoms Assess impact on quality of life Consider Dose Reduction If: Mild dysesthesia present but tolerable Patient achieving good weight loss (can afford slightly less efficacy) Symptoms are bothersome but not severe Consider Discontinuation If: Moderate to severe dysesthesia Progressive symptoms despite dose reduction Functional impairment Patient preference to stop Long-Term Unknowns and Research Needs Critical Questions for Future Studies 1

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Rapid fat loss can also cause loose skin, especially in people over 40 or those who lose a large amount of weight

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In a rat model of ISO-mediated myocardial infarction, CoQ10 preconditioning not only markedly expanded cardiac GSH levels and reduced the concentration of lipid peroxidation but also alleviated myocardial damage [177]

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