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Cells were treated with different concentrations (from 1 to 1000 M) of a NO synthesis inhibitorL-NAMEduring different times (12, 24, 48, 72, 96, and 120 h), with and without retreatment every 24 h (retreatment was applied to approximate this in vitro model to the chronic exposure that occurs in vivo)
L-carnitine plays a crucial role in the transportation of fatty acids into the cells to be burned as energy
The drug enhances insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning it stimulates insulin release only when blood glucose levels are elevated
Blood flow regulation: It may encourage angiogenesis, or the formation of new blood vessels, and support circulation in localized areas
Andrade C
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