Interactions between glutathione S-Transferase P1, tumor necrosis factor, and traffic-related air pollution for development of childhood allergic disease
(2025) 116:e23637
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In cohort studies, combination therapy was associated with a lower risk of MACE (RR 0.56 [95% CI 0.43, 0.71] and the kidney composite endpoint (RR 0.48 [95% CI 0.32, 0.73] relative to SGLT2 inhibitor or GLP-1 RA monotherapy
This is in part due to the beneficial bioactive polyphenols present in coffee