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GLP-1RAs significantly reduced HbA1c (MD: -1.13), weight (MD: -2.12) and FPG (MD: -31.44) levels as first-line therapy compared to placebo

This is problematic as patients with raised ICP and IIH have existent clinically relevant cognitive deficits and drug therapy which exacerbates cognitive function further compromises cognition

Rather than simply prescribing a GLP-1 and sending patients on their way, the program wraps medication into a comprehensive lifestyle framework that includes nutritional tracking, behavioral coaching, and the social accountability that has kept WeightWatchers relevant for over 60 years

Agency officials said this week that they have received reports of problems after patients used versions of semaglutide, the active ingredient in the brand-name medications, which have been compounded, or mixed in pharmacies

If refrigeration is temporarily unavailable, the medication should be kept in the coolest available location, avoiding direct sunlight and heat sources