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Astragalus polysaccharide regulates mir-182/bcl-2 axis to relieve metabolic memory through suppressing mitochondrial damage-mediated apoptosis in retinal pigment epithelial cells
Regulation of xCT expression and system x (c) (-) function in neuronal cells
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In the body, it plays a vital role in reducing oxidative stress, supporting detoxification and maintaining cell health
The RENAAL trial (N=1,513, mean follow-up 3.4 years) showed losartan reduced the risk of doubling serum creatinine by 25% compared to placebo over the long term, demonstrating net kidney protection despite the early apparent rise
METTL3 regulates the mRNA stability of TLR4, enhancing its translation and promoting the activation of TLR4 signaling, which drives neutrophil activation and function
