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Recentemente, o estudo TRIAL demonstrou uma incidncia menor de bito por causas renais, incio de terapia renal substitutiva de longo prazo (dilise ou transplante), TFGe persistente abaixo de 15 mL por minuto por 1,73 m 2 , reduo persistente de 50% na TFGe em comparao com o valor basal e incio de macroalbuminria persistente em pacientes tratados com semaglutida em comparao com placebo 47
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J Am Board Fam Med 26:203210 Meier JJ (2012) GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus
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