The most commonly observed side effects in the trial were nausea, diarrhea, and vomiting
Additionally, the research focused specifically on adults with both obesity and type 2 diabetes, so the findings may not apply to people using GLP-1 drugs solely for weight loss
The skyrocketing demand for drugs such as Ozempic and Mounjaro, which are approved for diabetes and widely used off-label for weight loss, has led to global supply problems and chronic shortages in Australia
A third obstacle is that zinc and copper ions exhibit the highest affinity for transition metal-binding sites and would occupy iron and manganese sites if the metals were present in freely exchangeable pools of similar concentrations (Irving and Williams, 1953)
Brier MR, Judge B, Ying C, Salter A, An H, Patel A, et al
Obesity is one of the drivers of this heartbreaking disparity